Frequently Asked Questions.
When would I use Staphage Lysate (SPL)® and on which dogs?
SPL® is indicated for the use on dogs with recurrent pyoderma. SPL® is not a primary treatment to initially eliminate the infection. Rather it is a treatment that prevents recurrence. SPL® can be initiated at the same time the primary treatment (topical treatment or antibiotics) is started.
What can I expect with Staphage Lysate (SPL)®?
When tested in a double-blinded placebo controlled study, SPL® demonstrated a 77% efficacy rate in recurrent canine pyoderma caused by Staphylococcus pseudintermedius. In addition, it has been shown to be effective in dogs with multi-resistant bacteria.
What are the common side effects of Staphage Lysate (SPL)®?
SPL® is a safe staphylococcal-derived substance and has very few side effects. Sometimes transient skin reactions appear at the injection site and consist of redness and/or itching. Rarely, SPL® may cause general vaccine type reaction (i.e. malaise, fever and/or chills). If excessive, these reactions may be lessened by dose reduction.
Are there any preservatives in Staphage Lysate (SPL)®?
No, there are no preservatives. This decreases the chance of allergic dogs developing allergies to the preservative.
How long does Staphage Lysate (SPL)® take to work?
SPL® begins to work in about 10 -12 weeks, shortly after the time that a 4 to 6 week regimen of antibotics wears off.
What can I use in the interim to alleviate itching, if necessary?
While antibiotic treatment is typically continued for 4-6 weeks and SPL® starts to work in 10-12 weeks, there is a possibility of some itching during this time period. While typically not a problem, more frequent bathing or other treatments can be used.
Does the length of treatment with antibiotics vary if I start Staphage Lysate (SPL)®?
Continue to use the antibiotic according to label.
Can Staphage Lysate (SPL)® be used concurrently with corticosteroids?
We do not recommend it. SPL® is a staphylococcal immunomodulator and stimulates T and B lymphocytes. Concurrent administration of corticosteroids – an immunosuppressant – may decrease the effectiveness of SPL®.
Is a MSDS required for Staphage Lysate (SPL)®?
No, a MSDS is not required since this product is a veterinary biologic and therefore regulated by the USDA. For further questions, please contact us at 800-562-5541.